Warning! OUTDATED BROWSER DETECTED!   Please update your browser immediately for a better experience on this website. Learn More
21/xsl/MobileMenu.xsltmobileNave880e1541/WorkArea//http://www.rsna.org/RSNANewsDetailWireframe.aspx?pageid=15319&id=22214&ekfxmen_noscript=1&ekfxmensel=falsefalsetruetruetruefalsefalse10-18.0.0.0730truefalse
  •  
     
  • Uterine Fibroid Embolization Helps Restore Fertility 



    June 13, 2017

    Conventional and partial uterine fibroid embolization (UFE) may be safe and effective outpatient procedures for women with uterine fibroids who want to conceive, according to new Radiology research.

    The study by João M. Pisco, MD, PhD, from the Department of Interventional Radiology at Saint Louis Hospital in Lisbon, Portugal, comprised 359 women. Researchers performed conventional UFE in 199 women between June 2004 and June 2009. Because some patients could not become pregnant in spite of evidence of a decrease in volume and complete ischemia of the fibroids, researchers hypothesized that a partial embolization could improve the pregnancy rate. Consequently, researchers performed partial UFE in the next 160 patients from June 2009 to June 2014.

    In conventional UFE, all uterine artery branches are embolized, while the partial procedure requires treatment of only the small vessels to the fibroids, leaving the corresponding larger vessels unaffected. Partial UFE may help reduce the risks of infertility associated with conventional UFE.

    After an average follow-up of almost six years, 149 of the 359 women, or 41.5 percent, had become pregnant one or more times, and 131 gave birth to a total of 150 babies. It was the first pregnancy for more than 85 percent of the women who gave birth.

    The procedures had a clinical success rate of approximately 79 percent for fibroid-related symptoms. Complication rates were 14.6 percent for partial UFE and 23.1 percent for conventional UFE. The procedure was repeated in 28 patients whose fibroids had not been fully treated, as shown by MRI, and 11 of those patients subsequently got pregnant.

    “Our findings show that UFE is a fertility-restoring procedure in women with uterine fibroids who wish to conceive, and pregnancy following UFE appears to be safe with low morbidity,” Dr. Pisco said. “Women who had been unable to conceive had normal pregnancies after UFE and similar complication rates as the general population in spite of being in a high-risk group.” 

     




    PiscoHeadshot
    Pisco

    PiscoFig1
     Digital subtraction angiography images show partial UFE. (a) Catheter is placed into right internal iliac artery with catheter tip in initial part of uterine artery (arrow); hypervascularization of fibroid is shown (arrowheads). (b) After partial UFE, uterine artery (arrow) is patent and there is some reduction of fibroid vessels, although some vessels are still shown (arrowheads). (c) Catheter is placed into left internal iliac artery with catheter tip in initial part of uterine artery (arrow); hypervascularization of fibroid is shown (arrowheads). (d) After partial UFE, uterine artery (arrow) is patent and there is some reduction of small fibroid vessels, although some vessels are still shown (arrowheads).

    Web Extras




    To:
    From:
    Subject:
    Comment:
    Link:
      
  •  
    comments powered by Disqus