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  • Radiology in Public Focus

    May 01, 2014

    Press releases were sent to the medical news media for the following articles appearing in recent issues of Radiology.

    Transverse gadolinium-enhanced T1-weighted MR images obtained superior to the carotid artery bifurcation
    (Click to enlarge) Transverse gadolinium-enhanced T1-weighted MR images obtained superior to the carotid artery bifurcation in a 72-year-old man. L = ICA lumen. (a) Low-signal-intensity calcium (arrow) and lipid core (arrowheads) can be seen. (b) Note contouring of the ICA. The outer adventitial wall (red), lipid core (blue), calcification (green) and vessel lumen (purple) are visible.
    (Radiology 2014;271;3:InPress) ©RSNA, 2014. All rights reserved. Printed with permission. 

    Carotid Artery Plaque Morphology and Composition in Relation to Incident Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis (MESA)

    Identification of vulnerable plaque characteristics with MR imaging aids in cardiovascular disease prediction and improves the reclassification of baseline cardiovascu­lar risk, new research shows.

    In the Multi-Ethnic Study of Atherosclerosis, Anna E. H. Zavodni, M.D., of the University of Toronto, Canada, and colleagues evaluated 946 participants using MR imaging and ultrasonog­raphy. Researchers used MR imaging to define carotid plaque composition and remodeling index (wall area divided by the sum of wall area and lumen area), while ultrasound was used to assess carotid wall thickness. Incident of cardiovascular events were ascertained for an average of 5.5 years. Multivariable Cox propor­tional hazards models, C statistics, and net reclassification improvement for event prediction were determined.

    Cardiovascular events occurred in 59 of the patients. Abnormal thickening of the carotid artery wall and the presence of a lipid core and calcium in the internal carotid artery on MR imaging were significant predictors of subsequent events. A lipid core was present in almost half of the patients who had an event, compared with only 17.8 percent of those who did not have an event.

    “The combination of MR imaging remodeling index and presence of lipid core resulted in improve­ment of the net reclassification index compared with traditional risk factors for cardiovascular disease events,” according to researchers.

    Images show axial spin-echo proton density of the substantia nigra (SN) (on the right) and gradient-recalled echo (GRE) (on the left)
    (Click to enlarge) Images show axial spin-echo proton density of the substantia nigra (SN) (on the right) and gradient-recalled echo (GRE) (on the left) of the SN at level I of an ex vivo brain sample in a 67-year-old woman. There is a triple-layered organization of the SN comparable to that showed in the in vivo images. Ventrally a low-signal-intensity layer (b) is attributable to the pars reticulata of the SN. In the middle part of the SN, a hyperintense band (c) corresponds to the ventral component of the pars compacta of the SN. The lateral part of this layer shows a high-signal-intensity spot (c1) corresponding to the oval shape hyperintensity of the in vivo three-dimensional multiecho susceptibility-weighted images that resemble the nigrosome formation. The dorsal hypointense layer visible on both spin-echo and GRE images (d) is referred to the dorsal component of the pars compacta of the SN. a = crus cerebri, e = brachjum conjunctivum, f = medial lemniscus, g = lateral lemniscus, h = central tegmental tract.
    (Radiology 2014;271;3:InPress) ©RSNA, 2014. All rights reserved. Printed with permission. 

    MR Imaging of the Substantia Nigra at 7 T Enables Diagnosis of Parkinson Disease

    MR imaging at 7 T reveals a three-layered organization of the substantia nigra (SN) in both the in-vivo and ex-vivo brainstem. The 3D multiecho susceptibility-weighted images can be used to accurately differentiate healthy patients from those with Parkinson’s disease, new research shows.

    Mirco Cosottini, M.D., of the University of Pisa, Italy, and colleagues described SN anatomy ex vivo on a gross brain specimen using highly resolved proton-density (spin-echo proton density) and gradient-recalled-echo (GRE) images, and in vivo in eight healthy subjects (mean age, 40.1 years) using GRE 3D multi­echo susceptibility-weighted images. After training on appearance of SN in eight healthy subjects, SN anat­omy was evaluated twice by two blinded observers in 13 healthy subjects (mean age, 54.7 years) and in 17 patients with Parkinson’s disease (mean age, 56.9 years).

    The abnormal architecture of the SN allowed researchers to discriminate between Parkinson’s patients and healthy subjects with a sensitivity and specificity of 100 percent and 96.2 percent respectively. Intraob­server agreement (k = 1) and interobserver agreement (k = 0.932) were excellent, results showed.

    “The identification of a radiologic marker of the altered SN by using 7-T MR imaging allows an imag­ing-based early diagnosis of Parkinson’s disease,” according to researchers. “A larger sample of patients would be desirable, but the high diag­nostic accuracy of the 7-T MR imaging in Parkinson’s patients enrolled in this study appears to be a promising result for a future broader clinical application.”

    Media Coverage of RSNA

    Radiology, March 2014In February, 595 RSNA-related news stories were tracked in the media. These stories reached an estimated 275 million people.

    Coverage included The New York Times, The Globe and Mail, Philly.com, The Providence Journal, ScienceDaily, Auntminnie.com, Healthfinder.gov, Applied Radiology and Medical News Today.

    Read coverage of RSNA in these media:

    New on RadiologyInfo.org

    RadiologyInfo.orgVisit RadiologyInfo.org to read the latest disease/condition topics posted to the site, including:

    RadiologyInfo.org Strategic Planning Sessions Lead to Change

    Be on the lookout for some exciting changes coming to RadiologyInfo.org, RSNA and ACR’s jointly-sponsored public information website.

    In February, the RadiologyInfo.org Strategic Planning Task Force met with a consultant who facilitated sessions to aid in developing a strategic plan. The RSNA-ACR Public Information Website Committee adopted a draft of the plan during its February meeting.

    With new goals and strategies now in place, changes will soon be implemented to better address the radiology information needs of patients, caretakers, radiologists, referring physicians and others.

    May Public Information Activities Focus on Stroke

    In recognition of American Stroke Month in May, RSNA is distributing public service announcements (PSAs) focusing on stroke imaging, interventional treatments for stroke and the importance of receiving stroke treatment quickly.

    The “60-Second Checkup” audio program focusing on carotid artery screening to detect stroke risk will be distributed to nearly 100 radio stations across the U.S.

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