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  • Your Donations in Action

    Quantification of Blood Spinal Cord Barrier Opening After MRI-guided Focused US

    July 25, 2018

    With limited therapeutic options, a spinal cord injury can leave patients with permanent paralysis. MRI-guided focused ultrasound (MRgFUS) is a novel non-invasive approach to disrupt glial scar formation, the reactive cellular process that occurs after injury to the central nervous system, and improve drug delivery to the injured spinal cord.

    2018 RSNA Research Medical Student Grant recipient Chloe Genevieve Cross, BSC, will work with scientific advisors, Yoshimi Anzai, MD, MPH, and Allison Payne, PhD, to investigate quantification methods to assess permeability of the blood-spinal cord barrier opening after MRgFUS in rodents.

    “I believe quantitative metrics in imaging remains an important factor to the future of radiology. I find these areas for application of quantitative imaging exciting and think these methods have wide-ranging potential. I am grateful to RSNA and its members for this grant and I look forward to this exciting research opportunity,” Cross said.

    “Thanks to the RSNA R&E Foundation, a brilliant medical student like Chloe can devote her summer to the establishment of a quantitative method for blood-spinal cord barrier,” Dr. Anzai said. “The research will help the future investigation of effective drug delivery for this devastating condition.”


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