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  • Quantitative Imaging Biomarkers Alliance

  • RSNA is committed to helping transform patient care by making radiology a more quantitative science.  

    What is Quantitative Imaging?

    Quantitative imaging is the extraction of quantifiable features from medical images for the assessment of normal or the severity, degree of change, or status of a disease, injury, or chronic condition relative to normal. Quantitative imaging includes the development, standardization, and optimization of anatomical, functional, and molecular imaging acquisition protocols, data analyses, display methods, and reporting structures. These features permit the validation of accurately and precisely obtained image-derived metrics with anatomically and physiologically relevant parameters, including treatment response and outcome, and the use of such metrics in research and patient care.  

    What is QIBA?

    QIBA is an initiative to advance quantitative imaging and the use of imaging biomarkers in clinical trials and clinical practice by engaging researchers, healthcare professionals and industry. This involves:

    • collaborating to identify needs, barriers, and solutions to develop and test consistent, reliable, valid, and achievable quantitative imaging results across imaging platforms, clinical sites, and time.
    • accelerating the development and adoption of hardware and software standards needed to achieve accurate and reproducible quantitative results from imaging methods.

    The Quantitative Imaging Biomarkers Alliance (QIBA) was organized by RSNA in 2007 to unite researchers, healthcare professionals and industry stakeholders in the advancement of quantitative imaging and the use of biomarkers in clinical trials and practice.

     QIBA Organizational Chart  

    QIBA Mission

    Improve the value and practicality of quantitative imaging biomarkers by reducing variability across devices, patients and time.

    The work of QIBA has advanced through the generous efforts of volunteer members from academia, the medical device, pharmaceutical and other business sectors, and government. There are four Modality Committees (Q-CT, Q-MR, Q-NM and Q-US) and 6 Technical Committees (CT Volumetry, COPD/Asthma, PDF-MRI, fMRI, FDG-PET & Ultrasound). All groups are open to interested persons. These Committees have specific tasks and deliverables for their respective modalities or disease-based approach.

  • Resources

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    QIBA Protocols and Profiles

    Learn about the Profiles and Protocols developed and implemented through QIBA Technical Committees.

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    QIBA Metrology Papers

    Learn more about the QIBA Metrology Working Group efforts to establish terminology and methodology guidelines for research use and clinical practice.

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    QIBA WIKI

    The QIBA WIKI is for collaborative creation of QIBA materials and ongoing activities.

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    QIBA Processes

    Understand the defined, coordinated process for developing and adopting standards-based biomarkers.

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    QIBA Newsletter

    Read articles and updates from technical committees and see how you can participate in QIBA-related activities.

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    Meeting Information and Resources

    Review presentations from RSNA and QIBA annual meetings and find resources from the IOM.