Archives of the AFIP -- RadioGraphics

Figure 2: High-grade intramedullary osteosarcoma of the proximal tibia in a 14-year-old boy with knee pain. (a-c) Anteroposterior (Panel A) and lateral (Panel B) radiographs and computed tomographic (CT) scan (Panel C) of the knee show a mixed lytic and blastic lesion with the sclerotic portion representing mineralized osteoid (arrowheads). (Panel D) Bone scan shows marked increased uptake of radionuclide in the tibial lesion. Additional increased uptake resulting from hyperemia is seen in the distal femur and about the ankle. (e-g) Coronal T1-weighted (Panel E) and axial T2-weighted (Panel F) MR images and photograph of the coronally sectioned gross specimen (Panel G) demonstrate the extent of intramedullary involvement including transphyseal spread (arrowheads) and a soft-tissue mass (arrows).

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