Archives of the AFIP -- RadioGraphics

Figure Legend | Panel A | Panel B | Panel C | Panel D

Figure 1: High-grade intramedullary osteosarcoma of the distal femur in a 15-year-old boy with knee pain and swelling. (Panel A) Anteroposterior radiograph of the knee shows extensive mineralized osteoid throughout the osteoblastic lesion, aggressive periosteal reaction (Codman triangle, arrowhead), and soft-tissue extension (arrows). (Panel B) Coronal T1-weighted magnetic resonance (MR) image obtained after intravenous administration of contrast material reveals the extent of enhancing marrow and soft-tissue involvement (arrows) and transphyseal spread of tumor (arrowheads) (the latter feature was not seen on radiographs). (Panel C) Photograph of the coronally sectioned gross specimen correlates well with the radiologic images, revealing the medullary (solid arrows) and soft-tissue (open arrows) extent as well as the transphyseal spread of tumor (*). (Panel D) Photomicrograph (original magnification, x150; hematoxylin-eosin stain) of the histologic specimen shows tumor cells that produced osteoid (arrows).

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