Archives of the AFIP -- RadioGraphics

Figure Legend | Panel A | Panel B | Panel C | Panel D

Figure 18: Secondary osteosarcoma of the humerus in a 77-year-old woman with long-standing Paget disease and new pain and a soft-tissue mass. (Panel A) Anteroposterior radiograph shows extensive underlying changes of Paget disease. Focal sclerosis in the medullary canal (arrows) and subtle calcification in the soft-tissue component (arrowheads) represent osteoid mineralization. (Panel B) Sagittal proton-density-weighted MR image reveals large intraosseous (arrows) and extraosseous (arrowheads) areas of malignant transformation. (c, d) Radiograph (Panel C) and photograph (Panel D) of the coronally sectioned gross specimen also show osteoid in the medullary and soft-tissue components (*) of the osteosarcoma, as well as underlying changes of Paget disease.

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