Archives of the AFIP -- RadioGraphics

Figure 11: Kaposi sarcoma of the esophagus and stomach in a 37-year-old homosexual man with AIDS who presented with abdominal pain, nausea, and vomiting. Panel A Single-contrast esophagogram shows multiple nodular masses (arrows) within the distal esophagus, near the gastroesophageal junction. The contours of these masses are smooth, a finding that is suggestive of their predominantly submucosal origin. Panel B Radiograph from an upper gastrointestinal series shows multiple mural masses with central ulceration (target or bull's-eye lesions) within the gastric antrum. Panel C Endoscopic photograph of the lesions within the gastric antrum shows two dark-red masses with central ulceration (arrow). Panel D Low-power photomicrograph (original magnification, X13.2; H-E stain) of the biopsy specimen from the stomach shows cellular infiltration of the lamina propria along with areas of hemorrhage and ulceration. Panel E High-power photomicrograph (original magnification, X100; H-E stain) shows the characteristic spindle-shaped cells (thick arrows) and multiple vascular clefts (thin arrows) of Kaposi sarcoma.

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