Archives of the AFIP -- RadioGraphics 1995; 15: 127-146

Figure Legend | Panel A | Panel B | Panel C

Figure 1: Adenoma-to-carcinoma sequence. This relatively slow evolution is illustrated in images obtained over a 9-year period in a patient who continuously refused treatment. Radiographs from barium enema studies demonstrate the evolution of a small, less than 2 cm, polypoid lesion (arrow in Panel A); to a larger, broader-based mass with associated puckering of the colonic wall (arrowheads in Panel B); to a broad-based polypoid mass narrowing the lumen by over 50% (arrows in Panel C); and eventually to distal large bowel obstruction. It was only the development of obstruction that prompted the patient's decision for surgery, which revealed that the tumor had penetrated through the muscularis mucosa and was associated with malignant adenopathy.

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